The Ultimate Guide To ceesdekker
The Ultimate Guide To ceesdekker
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Rotary movement of DNA rotors on nanopores. Leading row: Uncooked video clip of your Cy5 channel of every rotor. Middle row: corresponding solitary-particle localization outcomes of both of those ends with the DNA rotors. The placement of the present frame is marked as orange and blue dots, and also the trajectory of The ten frames prior to The existing frame is demonstrated as solid traces.
Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transportation of macromolecules
Dynamics of initiation, termination and reinitiation of DNA translocation because of the motor protein EcoR124I
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
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The coiled-coil of the human Rad50 DNA maintenance protein is made up of particular segments of amplified versatility
Considering the fact that 2000 he moved to solitary-molecule biophysics and nanobiology, with analysis from DNA supercoiling research of nucleosomes and DNA repair proteins to DNA translocation as a result of nanopores. Not long ago his analysis has focused on researching cell division with microbes on chip, even though his greatest desire is from the path of realizing artificial cells.
2000, discovery that nanotubes can have extraordinary massive present-day densities; settled the controversial challenge of Digital transport by way of DNA molecules by measurements of insulating actions at the single molecule degree; and demonstration of the AFM system for single-molecule manipulation of nanotubes
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Resolving the step size in condensin-driven DNA loop extrusion identifies ATP binding as the step-generating process
An integrated microfluidic platform for quantifying drug permeation across biomimetic vesicle membranes
Several new phenomena were learned, and he and his investigation group recognized a leading posture In this particular field of exploration. Dekker and his analysis team identified new physics of nanotubes as well as explored the feasibility of molecular electronics. In 1998, they have been the first to develop a transistor according to one nanotube molecule.
For example, we think about the nucleopore advanced, a gateway amongst the cell nucleus as well as cytoplasm. This is ceesdekker.net an extremely difficult program and thus difficult to review in the cell, so we use biomimetics. We reconstruct holes after which you can insert specific components of the nucleopore advanced to review transportation by way of it at the single-molecule stage.’
Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij satisfied enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond smart design in 2005. (nl)